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Index > Protein center > PYCR2(Gene name) > Human
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  • PYCR2 (Gene name),
  • Pyrroline-5-carboxylate reductase 2 (Protein name ),  P5CR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PYCR2;
    Protein name:
    Pyrroline-5-carboxylate reductase 2(P5C reductase 2;P5CR 2);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodecamer; composed of 5 homodimers.
    Function:
    Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    320
    Sequence:
    50:
    MSVGFIGAGQ | LAYALARGFT | AAGILSAHKI | IASSPEMNLP | TVSALRKMGV | 
    100:
    NLTRSNKETV | KHSDVLFLAV | KPHIIPFILD | EIGADVQARH | IVVSCAAGVT | 
    150:
    ISSVEKKLMA | FQPAPKVIRC | MTNTPVVVQE | GATVYATGTH | ALVEDGQLLE | 
    200:
    QLMSSVGFCT | EVEEDLIDAV | TGLSGSGPAY | AFMALDALAD | GGVKMGLPRR | 
    250:
    LAIQLGAQAL | LGAAKMLLDS | EQHPCQLKDN | VCSPGGATIH | ALHFLESGGF | 
    300:
    RSLLINAVEA | SCIRTRELQS | MADQEKISPA | ALKKTLLDRV | KLESPTVSTL | 
    320:
    TPSSPGKLLT | RSLALGGKKD | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human P5C reductase 2
    Cat.:
    E7707h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human P5C reductase 2
    Cat.:
    E7707b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human P5C reductase 2
    Cat.:
    E7707r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human P5C reductase 2
    Cat.:
    E7707m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human P5C reductase 2
    Cat.:
    U7707h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human P5C reductase 2
    Cat.:
    U7707b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human P5C reductase 2
    Cat.:
    U7707m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human P5C reductase 2
    Cat.:
    U7707r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human P5C reductase 2
    Cat.:
    P7707Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human P5C reductase 2
    Cat.:
    P7707Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human P5C reductase 2
    Cat.:
    P7707Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human P5C reductase 2
    Monoclonal Antibody for Human P5C reductase 2
    Monoclonal Antibody for Human P5C reductase 2
    Monoclonal Antibody for Human P5C reductase 2
    Monoclonal Antibody for Human P5C reductase 2
    Protein for Human P5C reductase 2
    Protein for Human P5C reductase 2
    Protein for Human P5C reductase 2
    Protein for Human P5C reductase 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of a new human cDNA homologous to human pyrroline 5-carboxylate reductase mRNA."
      Yue P. , Yu L. , Zhao S.Y.
      Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cervix.
      tissue: Skin.
    6. 6.
      Bienvenut W.V. , Heiserich L. , Gottlieb E. , Zebisch A. , Kolch W.
      Submitted (2008-10) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-17;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
    7. 7.
      "Pyrroline-5-carboxylate reductase in human erythrocytes."
      Yeh G.C. , Harris S.C. , Phang J.M.
      J. Clin. Invest.67:1042-1046(1981) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;TISSUE SPECIFICITY
    8. 8.
      "Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH."
      Merrill M.J. , Yeh G.C. , Phang J.M.
      J. Biol. Chem.264:9352-9358(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBUNIT;SUBCELLULAR LOCATION;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY
    9. 9.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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